Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 20/20 | 0.70 |
| ▸ | ERBB2 | P04626 | 17/20 | 0.70 |
| ▸ | SRC | P12931 | 1/20 | 0.57 |
| ▸ | KDR | P35968 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14854790 | 1.00 | EGFR (0.70) | EGFRERBB2SRCKDR | |
| SCHEMBL18933572 | 0.95 | EGFR (0.68) | EGFRERBB2SRCKDR | |
| SCHEMBL15222038 | 0.95 | EGFR (0.68) | EGFRERBB2SRCKDR | |
| SCHEMBL18933553 | 0.95 | EGFR (0.70) | EGFRERBB2 | |
| SCHEMBL15222037 | 0.95 | EGFR (0.70) | EGFRERBB2 | |
| SCHEMBL14854924 | 0.93 | EGFR (0.79) | EGFRERBB2SRCKDR | |
| SCHEMBL14854926 | 0.93 | EGFR (0.79) | EGFRERBB2SRCKDR | |
| SCHEMBL14855197 | 0.93 | EGFR (0.79) | EGFRERBB2SRCKDR | |
| SCHEMBL14855198 | 0.93 | EGFR (0.79) | EGFRERBB2SRCKDR | |
| SCHEMBL15222047 | 0.93 | EGFR (0.67) | EGFRERBB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3222620-B1 | CYANOQUINOLINE DERIVATIVES | TIANJIN HEMAY ONCOLOGY PHARMACEUTICAL CO LTD (CN) | 2019-11-20 | — | — | EP | disclosed |
| EP-3222620-A1 | CYANOQUINOLINE DERIVATIVES | TIANJIN HEMAY ONCOLOGY PHARMACEUTICAL CO., LTD. (CN) | 2017-09-27 | — | — | EP | disclosed |
| EP-2581372-B1 | CYANOQUINOLINE DERIVATIVES | TIANJIN HEMAY ONCOLOGY PHARMACEUTICAL CO LTD (CN) | 2017-06-07 | — | — | EP | disclosed |