⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11584713 | 0.81 | — | — | |
| SCHEMBL3817904 | 0.74 | — | — | |
| SCHEMBL7187060 | 0.71 | — | — | |
| SCHEMBL28174812 | 0.69 | — | — | |
| SCHEMBL115447 | 0.69 | CYP3A4 (0.33) | — | |
| SCHEMBL9307560 | 0.69 | — | — | |
| SCHEMBL548695 | 0.69 | — | — | |
| SCHEMBL30626777 | 0.69 | — | — | |
| SCHEMBL28006187 | 0.69 | — | — | |
| SCHEMBL2657767 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8758725-B2 | Perylenequinone derivatives and uses thereof | QUEST PHARMATECH INC. (CA) | 2014-06-24 | — | — | US | disclosed |
| US-8747811-B2 | Perylenequinone derivatives and uses thereof | QUEST PHARMATECH INC. (CA) | 2014-06-10 | — | — | US | disclosed |
| US-20140072512-A1 | PERYLENEQUINONE DERIVATIVES AND USES THEREOF | QUEST PHARMATECH, INC. (CA) | 2014-03-13 | — | — | US | disclosed |
| US-20130304089-A1 | PERYLENEQUINONE DERIVATIVES AND USES THEREOF | QUEST PHARMATECH INC. (CA) | 2013-11-14 | — | — | US | disclosed |
| US-8506931-B2 | Perylenequinone derivatives and uses thereof | QUEST PHARMATECH INC. (CA) | 2013-08-13 | — | — | US | disclosed |
| EP-1868717-B1 | MANUFACTURE OF THIOLACTONES | DSM IP ASSETS BV (NL) | 2013-03-27 | — | — | EP | disclosed |
| EP-1866081-B1 | MANUFACTURE OF LACTONES | DSM IP ASSETS BV (NL) | 2013-01-30 | — | — | EP | disclosed |
| US-8344161-B2 | Process for the preparation of pyrollidine-3-carboxylic acids | HOFFMANN-LA ROCHE INC. (US) | 2013-01-01 | — | — | US | disclosed |
| US-8008346-B2 | Chemotherapeutic agents for inhibition of protein translation | The Royal University for the Advancement of Learning/McGill University (CA) | 2011-08-30 | — | — | US | disclosed |
| US-7935829-B2 | Manufacture of thiolactones | DSM IP ASSETS B.V. (NL) | 2011-05-03 | — | — | US | disclosed |
| EP-1465885-A2 | NOVEL ALKYL/ARYL HYDROXY OR KETO THIEPINE COMPOUNDS AS INHIBITORS OF APICAL SODIUM CO-DEPENDENT BILE ACID TRANSPORT (ASBT) AND TAUROCHOLATE UPTAKE | Pharmacia Corporation (US) | 2004-10-13 | — | — | EP | disclosed |
| US-20040176438-A1 | Novel mono- and di-fluorinated beozothiepine copmunds as inhibitors of apical sodium co-dependent bile acid transport (ASBT) and taurocholate uptake | G.D. SEARLE, LLC | 2004-09-09 | — | — | US | disclosed |
| EP-1448546-A1 | NOVEL MONO- AND DI-FLUORINATED BENZOTHIEPINE COMPOUNDS AS INHIBITORS OF APICAL SODIUM CO-DEPENDENT BILE ACID TRANSPORT (ASBT) AND TAUROCHOLATE UPTAKE | G.D. Searle LLC (US) | 2004-08-25 | — | — | EP | disclosed |
| US-6740663-B2 | ANTIHYPERLIPIDEMIC AGENTS | G.D. SEARLE, LLC | 2004-05-25 | — | — | US | disclosed |
| US-20040067872-A1 | Novel mono- and di-fluorinated benzothiepine compouds as inhibitors of apical sodium co-dependent bile acid transport (ASBT) and taurocholate uptake | G.D. SEARLE, LLC (US) | 2004-04-08 | — | — | US | disclosed |
| US-20030195218-A1 | Novel alkyl/aryl hydroxy or keto thiepine compounds as inhibitors of apical sodium co-dependent bile acid transport (ASBT) and taurocholate uptake | PHARMACIA CORPORATION | 2003-10-16 | — | — | US | disclosed |
| WO-2003061604-A2 | NOVEL ALKYL/ARYL HYDROXY OR KETO THIEPINES. | PHARMACIA CORPORATION (US) | 2003-07-31 | — | — | WO | disclosed |
| WO-2003040127-A1 | NOVEL MONO- AND DI-FLUORINATED BENZOTHIEPINE COMPOUNDS AS INHIBITORS OF APICAL SODIUM CO-DEPENDENT BILE ACID TRANSPORT (ASBT) AND TAUROCHOLATE UPTAKE | G.D. SEARLE LLC (US) | 2003-05-15 | — | — | WO | disclosed |
| EP-1091943-A1 | NON-PEPTIDYL INHIBITORS OF VLA-4 DEPENDENT CELL BINDING USEFUL IN TREATING INFLAMMATORY, AUTOIMMUNE, AND RESPIRATORY DISEASES | Pfizer Products Inc. (US) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000000477-A1 | NON-PEPTIDYL INHIBITORS OF VLA-4 DEPENDENT CELL BINDING USEFUL IN TREATING INFLAMMATORY, AUTOIMMUNE, AND RESPIRATORY DISEASES | PFIZER PRODUCTS INC. (US) | 2000-01-06 | — | — | WO | disclosed |