Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAGLA | Q9Y4D2 | 17/20 | 0.56 |
| ▸ | DAGLB | Q8NCG7 | 8/20 | 0.56 |
| ▸ | DDHD2 | O94830 | 1/20 | 0.54 |
| ▸ | ABHD6 | Q9BV23 | 7/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18935818 | 0.87 | DAGLA (0.61) | DAGLADAGLBDDHD2ABHD6 | |
| SCHEMBL18935815 | 0.87 | DAGLA (0.61) | DAGLADAGLBDDHD2ABHD6 | |
| SCHEMBL18935822 | 0.84 | DAGLA (0.63) | DAGLADAGLBDDHD2ABHD6 | |
| SCHEMBL18921300 | 0.84 | DAGLA (0.63) | DAGLADAGLBDDHD2ABHD6 | |
| SCHEMBL18935825 | 0.84 | DAGLA (0.63) | DAGLADAGLBDDHD2ABHD6 | |
| SCHEMBL18936215 | 0.84 | DAGLA (0.67) | DAGLADAGLBDDHD2ABHD6 | |
| SCHEMBL18936213 | 0.84 | DAGLA (0.67) | DAGLADAGLBDDHD2ABHD6 | |
| SCHEMBL18936205 | 0.84 | DAGLA (0.67) | DAGLADAGLBDDHD2ABHD6 | |
| SCHEMBL18935645 | 0.82 | DAGLA (0.61) | DAGLADAGLBDDHD2ABHD6 | |
| SCHEMBL18921254 | 0.82 | DAGLA (0.58) | DAGLADAGLBDDHD2ABHD6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017096315-A1 | TRIAZOLE DAGL(α) INHIBITORS | THE SCRIPPS RESEARCH INSTITUTE (US) | 2017-06-08 | — | — | WO | disclosed |