Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 7/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.59 |
| ▸ | FAAH | O00519 | 2/20 | 0.56 |
| ▸ | CNR2 | P34972 | 3/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.46 |
| ▸ | RXRA | P19793 | 2/20 | 0.46 |
| ▸ | PPARG | P37231 | 2/20 | 0.46 |
| ▸ | OXER1 | Q8TDS5 | 2/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | PPARA | Q07869 | 2/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.41 |
| ▸ | F7 | P08709 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | F3 | P13726 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2191225 | 1.00 | CNR1 (0.59) | CNR1ALDH1A1FAAHCNR2ALOX12 | |
| SCHEMBL2188464 | 0.96 | CNR1 (0.64) | CNR1ALDH1A1FAAHCNR2ALOX12 | |
| SCHEMBL12417778 | 0.96 | CNR1 (0.64) | CNR1ALDH1A1FAAHCNR2ALOX12 | |
| SCHEMBL2188466 | 0.96 | CNR1 (0.64) | CNR1ALDH1A1FAAHCNR2ALOX12 | |
| SCHEMBL18936853 | 0.92 | CNR1 (0.61) | CNR1ALDH1A1FAAHCNR2ALOX12 | |
| SCHEMBL2189105 | 0.92 | CNR1 (0.61) | CNR1ALDH1A1FAAHCNR2ALOX12 | |
| SCHEMBL2191834 | 0.90 | CNR1 (0.71) | CNR1ALDH1A1FAAHCNR2ALOX12 | |
| SCHEMBL18936851 | 0.88 | CNR1 (0.66) | CNR1ALDH1A1FAAHCNR2ALOX12 | |
| SCHEMBL2190833 | 0.88 | CNR1 (0.66) | CNR1ALDH1A1FAAHCNR2ALOX12 | |
| SCHEMBL2189516 | 0.87 | CNR1 (0.57) | CNR1ALDH1A1FAAHCNR2ALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2521447-B1 | FATTY ACID FUMARATE DERIVATIVES AND THEIR USES | CATABASIS PHARMACEUTICALS INC (US) | 2017-06-14 | — | — | EP | claimed |