Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | NOS1 | P29475 | 1/20 | 0.30 |
| ▸ | NOS2 | P35228 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18937148 | 1.00 | CYP1A2 (0.40) | CYP1A2NOS1NOS2 | |
| SCHEMBL1419553 | 1.00 | CYP1A2 (0.40) | CYP1A2NOS1NOS2 | |
| SCHEMBL11705481 | 0.94 | EPHX1 (0.35) | CYP1A2 | |
| SCHEMBL1911580 | 0.94 | EPHX1 (0.35) | CYP1A2 | |
| SCHEMBL14153027 | 0.94 | EPHX1 (0.35) | CYP1A2 | |
| SCHEMBL10620419 | 0.92 | EPHX1 (0.38) | CYP1A2 | |
| SCHEMBL7711924 | 0.92 | EPHX1 (0.38) | CYP1A2 | |
| SCHEMBL12161640 | 0.92 | EPHX1 (0.38) | CYP1A2 | |
| SCHEMBL14976126 | 0.92 | EPHX1 (0.38) | CYP1A2 | |
| SCHEMBL10773640 | 0.92 | EPHX1 (0.38) | CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2560976-B9 | FUROPYRIDINE COMPOUNDS AND USES THEREOF | NOVARTIS AG (CH) | 2017-06-07 | — | — | EP | disclosed |