Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BLM | P54132 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | AHR | P35869 | 3/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.34 |
| ▸ | GAPDH | P04406 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HSPA1A | P0DMV8 | 1/20 | 0.34 |
| ▸ | MIF | P14174 | 1/20 | 0.34 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | PYGL | P06737 | 1/20 | 0.31 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10197527 | 0.79 | AR (0.40) | BLMLMNAMAPTHTTAHR | |
| SCHEMBL34463405 | 0.79 | AR (0.40) | BLMLMNAMAPTHTTAHR | |
| SCHEMBL19423744 | 0.79 | CYP19A1 (0.38) | BLMMAPTADRA2AMEN1KMT2A | |
| SCHEMBL20888295 | 0.79 | CYP19A1 (0.38) | BLMMAPTADRA2AMEN1KMT2A | |
| SCHEMBL19423528 | 0.76 | CYP3A4 (0.34) | — | |
| SCHEMBL28384551 | 0.76 | CYP19A1 (0.35) | BLMLMNAMAPTHTTAHR | |
| SCHEMBL17363828 | 0.75 | FFAR1 (0.40) | BLMMEN1KMT2ACYP19A1PLA2G1B | |
| SCHEMBL17363943 | 0.75 | FFAR1 (0.40) | BLMMEN1KMT2ACYP19A1PLA2G1B | |
| SCHEMBL17363928 | 0.75 | FFAR1 (0.40) | BLMMEN1KMT2ACYP19A1PLA2G1B | |
| SCHEMBL19429589 | 0.74 | GAA (0.46) | LMNAMAPTHTTADRA2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3027601-B1 | SYK INHIBITORS | GILEAD SCIENCES INC (US) | 2017-10-25 | — | — | EP | disclosed |
| WO-2017093545-A1 | ANTI-BACTERIAL COMPOUNDS BASED ON AMINO-GOLD PHOSPHINE COMPLEXES | AUSPHERIX LIMITED (GB) | 2017-06-08 | — | — | WO | disclosed |