Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.66 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9784389 | 0.88 | CHRM2 (0.72) | CHRM2MEN1KMT2ACYP3A4CYP2D6 | |
| SCHEMBL5529492 | 0.86 | CYP3A4 (0.58) | CHRM2MEN1KMT2ACYP3A4CYP2D6 | |
| SCHEMBL11922779 | 0.86 | CHRM2 (0.76) | CHRM2MEN1KMT2ACYP3A4CYP2D6 | |
| SCHEMBL2471147 | 0.85 | CHRM2 (0.62) | CHRM2MEN1KMT2ACYP3A4CYP2D6 | |
| SCHEMBL23202539 | 0.85 | CHRM2 (0.49) | CHRM2MEN1KMT2ACYP3A4CYP2D6 | |
| SCHEMBL27830999 | 0.85 | CHRM2 (0.79) | CHRM2MEN1KMT2ACYP3A4CYP2D6 | |
| SCHEMBL11311265 | 0.85 | CHRM2 (0.79) | CHRM2MEN1KMT2ACYP3A4CYP2D6 | |
| SCHEMBL6072254 | 0.84 | CHRM2 (0.72) | CHRM2MEN1KMT2ACYP3A4CYP2D6 | |
| SCHEMBL22762073 | 0.84 | TAAR1 (0.63) | CHRM2MEN1KMT2ACYP3A4CYP2D6 | |
| SCHEMBL23368473 | 0.83 | MEN1 (0.48) | CHRM2MEN1KMT2ACYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017096045-A1 | MULTIVALENT RAS BINDING COMPOUNDS | KYRAS THERAPEUTICS, INC. (US) | 2017-06-08 | — | — | WO | disclosed |