SCHEMBL18940463

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL20593092	0.86	P4HTM (0.52)	MAPK1PSEN1PSEN2APH1BNCSTN
	SCHEMBL8593499	0.86	PTPN1 (0.43)	PSEN1PSEN2APH1BNCSTNAPH1A
	SCHEMBL31286721	0.83	MAPK1 (0.43)	MAPK1
	SCHEMBL22371614	0.82	MAPK1 (0.43)	MAPK1L3MBTL1KDM4ERAB9AGPR119
	SCHEMBL21200606	0.82	LCK (0.44)	MAPK1PSEN1PSEN2APH1BNCSTN
	SCHEMBL8555283	0.82	PTPN1 (0.41)	PSEN1PSEN2APH1BNCSTNAPH1A
	SCHEMBL25247080	0.82	GAA (0.51)	MAPK1KDM4EGAAALDH1A1
	SCHEMBL30404318	0.82	GAA (0.51)	MAPK1KDM4EGAAALDH1A1
	SCHEMBL23397123	0.81	P4HTM (0.52)	PTPN1L3MBTL1KDM4EMEN1KMT2A
	SCHEMBL18940415	0.81	MAPK1 (0.56)	MAPK1L3MBTL1KDM4EMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.