⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10282652 | 1.00 | — | — | |
| SCHEMBL10282535 | 1.00 | — | — | |
| SCHEMBL19399590 | 0.83 | TDP1 (0.33) | — | |
| SCHEMBL10282636 | 0.81 | — | — | |
| SCHEMBL20999459 | 0.81 | — | — | |
| SCHEMBL13743167 | 0.81 | — | — | |
| SCHEMBL10282653 | 0.81 | — | — | |
| SCHEMBL24177621 | 0.80 | KDM4E (0.40) | — | |
| SCHEMBL24177276 | 0.77 | TSHR (0.38) | — | |
| SCHEMBL27325464 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250223392-A1 | HYDROPHILIZED POLYDIORGANOSILOXANE VINYLIC CROSSLINKERS AND USES THEREOF | ALCON INC (CH) | 2025-07-10 | — | — | US | disclosed |
| US-12286501-B2 | Hydrophilized polydiorganosiloxane vinylic crosslinkers and uses thereof | ALCON INC. (CH) | 2025-04-29 | — | — | US | disclosed |
| US-20250059330-A1 | SILICONE HYDROGEL CONTACT LENSES | ALCON INC (CH) | 2025-02-20 | — | — | US | disclosed |
| EP-4481478-A2 | SILICONE HYDROGEL CONTACT LENSES | Alcon Inc. (CH) | 2024-12-25 | — | — | EP | disclosed |
| US-12162987-B2 | Silicone hydrogel contact lenses | ALCON INC. (CH) | 2024-12-10 | — | — | US | disclosed |
| EP-4235274-B1 | SILICONE HYDROGEL CONTACT LENSES | ALCON INC (CH) | 2024-10-09 | — | — | EP | disclosed |
| US-20240254269-A1 | HYDROPHILIZED POLYDIORGANOSILOXANE VINYLIC CROSSLINKERS AND USES THEREOF | ALCON INC. (CH) | 2024-08-01 | — | — | US | disclosed |
| US-11926689-B2 | Hydrophilized polydiorganosiloxane vinylic crosslinkers and uses thereof | ALCON INC. (CH) | 2024-03-12 | — | — | US | disclosed |
| US-20240018309-A1 | SILICONE HYDROGEL CONTACT LENSES | ALCON INC. (CH) | 2024-01-18 | — | — | US | disclosed |
| US-11802182-B2 | Silicone hydrogel contact lenses | ALCON INC. (CH) | 2023-10-31 | — | — | US | disclosed |
| US-10246543-B2 | Hydrophilized polydiorganosiloxane vinylic crosslinkers and uses thereof | NOVARTIS AG (CH) | 2019-04-02 | — | — | US | disclosed |
| US-20180362697-A1 | HYDROPHILIZED POLYDIORGANOSILOXANE VINYLIC CROSSLINKERS AND USES THEREOF | ALCON INC. (CH) | 2018-12-20 | — | — | US | disclosed |
| US-20180355112-A1 | SILICONE HYDROGEL CONTACT LENSES | ALCON INC. (CH) | 2018-12-13 | — | — | US | disclosed |
| WO-2018224976-A1 | SILICONE HYDROGEL CONTACT LENSES | NOVARTIS AG (CH) | 2018-12-13 | — | — | WO | disclosed |
| EP-3390498-A1 | HYDROPHILIZED POLYDIORGANOSILOXANE VINYLIC CROSSLINKERS AND USES THEREOF | Novartis AG (CH) | 2018-10-24 | — | — | EP | disclosed |
| US-10081697-B2 | Hydrophilized polydiorganosiloxane vinylic crosslinkers and uses thereof | NOVARTIS AG (CH) | 2018-09-25 | — | — | US | disclosed |
| CN-108473681-A | Hydrophilized polydiorganosiloxane vinyl crosslinkers and uses thereof | 诺华股份有限公司 | 2018-08-31 | — | — | CN | disclosed |
| WO-2017103790-A1 | HYDROPHILIZED POLYDIORGANOSILOXANE VINYLIC CROSSLINKERS AND USES THEREOF | NOVARTIS AG (CH) | 2017-06-22 | — | — | WO | disclosed |
| US-20170166673-A1 | HYDROPHILIZED POLYDIORGANOSILOXANE VINYLIC CROSSLINKERS AND USES THEREOF | ALCON INC. (CH) | 2017-06-15 | — | — | US | disclosed |
| CN-104684887-B | Method for producing 2- (ethylamino) ethanol | 广荣化学工业株式会社 | 2017-03-08 | — | — | CN | disclosed |