Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNT1 | O60563 | 18/20 | 1.00 |
| ▸ | CCNA2 | P20248 | 18/20 | 1.00 |
| ▸ | CDK2 | P24941 | 18/20 | 1.00 |
| ▸ | CDK9 | P50750 | 18/20 | 1.00 |
| ▸ | PDPK1 | O15530 | 2/20 | 0.72 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.65 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.65 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.65 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.63 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.63 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1843060 | 0.89 | CCNT1 (0.80) | CCNT1CCNA2CDK2CDK9PDPK1 | |
| SCHEMBL18942004 | 0.85 | CCNT1 (1.00) | CCNT1CCNA2CDK2CDK9PDPK1 | |
| SCHEMBL18941999 | 0.84 | CCNT1 (1.00) | CCNT1CCNA2CDK2CDK9PDPK1 | |
| SCHEMBL12763393 | 0.84 | CCNT1 (0.78) | CCNT1CCNA2CDK2CDK9 | |
| SCHEMBL1603418 | 0.84 | PDPK1 (1.00) | CCNT1CCNA2CDK2CDK9PDPK1 | |
| SCHEMBL12657429 | 0.83 | CCNT1 (0.71) | CCNT1CCNA2CDK2CDK9PDPK1 | |
| SCHEMBL18941884 | 0.82 | CCNT1 (0.79) | CCNT1CCNA2CDK2CDK9PDPK1 | |
| SCHEMBL18941987 | 0.82 | CCNT1 (1.00) | CCNT1CCNA2CDK2CDK9PDPK1 | |
| SCHEMBL18941992 | 0.82 | CCNT1 (1.00) | CCNT1CCNA2CDK2CDK9DYRK1A | |
| SCHEMBL12572867 | 0.81 | CCNT1 (0.69) | CCNT1CCNA2CDK2CDK9PDPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3383875-B1 | 3-PYRIMIDINYL PYRROLO [2,3-B] PYRIDINE AS ANTICANCER AGENTS AND THE PROCESS FOR THE PREPARATION THEREOF | COUNCIL SCIENT IND RES (IN) | 2022-02-09 | — | — | EP | disclosed |
| WO-2017094026-A1 | 3-PYRIMIDINYL PYRROLO [2,3-B] PYRIDINE AS NEW ANTICANCER AGENTS AND THE PROCESS FOR THE PREPARATION THEREOF | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2017-06-08 | — | — | WO | disclosed |