Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 4/20 | 0.41 |
| ▸ | CREBBP | Q92793 | 3/20 | 0.41 |
| ▸ | LRRK2 | Q5S007 | 3/20 | 0.39 |
| ▸ | ACVR1 | Q04771 | 2/20 | 0.39 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.39 |
| ▸ | FER | P16591 | 1/20 | 0.39 |
| ▸ | LTK | P29376 | 1/20 | 0.39 |
| ▸ | CDK8 | P49336 | 1/20 | 0.39 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.39 |
| ▸ | ROS1 | P08922 | 1/20 | 0.36 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | CSNK1G1 | Q9HCP0 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | BRPF1 | P55201 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5697347 | 0.66 | ACVR1 (0.67) | CREBBPLRRK2ACVR1PDGFRAFER | |
| SCHEMBL8590983 | 0.65 | ACVR1 (0.44) | BRD4CREBBPLRRK2ACVR1PDGFRA | |
| SCHEMBL12220595 | 0.62 | ACVR1 (0.50) | BRD4CREBBPLRRK2ACVR1PDGFRA | |
| SCHEMBL11168286 | 0.62 | ACVR1 (0.41) | BRD4CREBBPLRRK2ACVR1PDGFRA | |
| SCHEMBL4896663 | 0.60 | ACVR1 (0.42) | LRRK2ACVR1PDGFRAFERLTK | |
| SCHEMBL9793275 | 0.60 | ACVR1 (0.47) | BRD4CREBBPLRRK2ACVR1PDGFRA | |
| SCHEMBL11180043 | 0.59 | CREBBP (0.39) | BRD4CREBBPLRRK2ACVR1PDGFRA | |
| SCHEMBL12242976 | 0.59 | ACVR1 (0.56) | CREBBPLRRK2ACVR1PDGFRAFER | |
| SCHEMBL677636 | 0.58 | BRD4 (1.00) | BRD4CREBBPNPC1MAPK13MAPK12 | |
| SCHEMBL23484522 | 0.58 | CREBBP (0.47) | BRD4CREBBPLRRK2ACVR1PDGFRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1781661-B1 | VASOPRESSIN V1A ANTAGONISTS | VANTIA LTD (GB) | 2017-06-07 | — | — | EP | disclosed |