Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 3/20 | 0.65 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.31 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.31 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.31 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.31 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.31 |
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.30 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.30 |
| ▸ | CSF1R | P07333 | 1/20 | 0.30 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9903456 | 0.79 | GRM5 (1.00) | GRM5TNIK | |
| SCHEMBL24463055 | 0.77 | GRM5 (0.61) | GRM5DYRK1AADORA2AADORA1YTHDC1 | |
| SCHEMBL27072911 | 0.77 | GRM5 (0.61) | GRM5DYRK1AGABRA1GABRG2GABRB3 | |
| SCHEMBL9903377 | 0.76 | GRM5 (0.73) | GRM5TNIK | |
| SCHEMBL18946091 | 0.75 | GRM5 (0.68) | GRM5GABRA1GABRA5 | |
| SCHEMBL9903825 | 0.73 | GRM5 (0.72) | GRM5 | |
| SCHEMBL10238681 | 0.72 | GRM5 (0.50) | GRM5DYRK1AADORA2AADORA1YTHDC1 | |
| SCHEMBL20641223 | 0.72 | GRM5 (0.51) | GRM5DYRK1AGABRA1GABRG2GABRB3 | |
| SCHEMBL9994861 | 0.71 | GRM5 (0.43) | GRM5GABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL24463610 | 0.70 | KDM4E (0.35) | GRM5GABRA1GABRG2GABRB3GABRA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111416154-B | Silicon-based pyridine additive for high-voltage lithium ion battery electrolyte, electrolyte and battery | 松山湖材料实验室 | 2021-08-06 | — | — | CN | claimed |
| CN-111416154-A | Silicon-based pyridine additive for high-voltage lithium ion battery electrolyte, electrolyte and battery | 松山湖材料实验室 | 2020-07-14 | — | — | CN | claimed |
| CN-116057045-A | Fibroblast growth factor receptor kinase inhibitors | 金耐特生物制药公司 | 2023-05-02 | — | — | CN | disclosed |
| EP-4161656-A1 | INHIBITORS OF FIBROBLAST GROWTH FACTOR RECEPTOR KINASES | Kinnate Biopharma Inc. (US) | 2023-04-12 | — | — | EP | disclosed |
| US-11345681-B1 | Inhibitors of fibroblast growth factor receptor kinases | KINNATE BIOPHARMA INC. (US) | 2022-05-31 | — | — | US | disclosed |
| WO-2017093544-A1 | ALKYNYL PHOSPHINE GOLD COMPLEXES FOR TREATING BACTERIAL INFECTIONS | AUSPHERIX LIMITED (GB) | 2017-06-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11345681-B1 | Inhibitors of fibroblast growth factor receptor kinases | FGFR1, FGFR2, FGFR3 | GRM5 2790/4885DYRK1A 967/4885ADORA2A 2538/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.