SCHEMBL18948161

SCHEMBL18948161

CC(C)[C@@H]1C[C@@H](N)CN1C(C)(C)C

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
HTT P42858 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19454380 0.77 HTT (0.34) HTT
SCHEMBL23025203 0.77
SCHEMBL21159690 0.75
SCHEMBL19239946 0.75 PIK3CD (0.32)
SCHEMBL18827593 0.75
SCHEMBL24967893 0.75 HTT (0.41) HTT
SCHEMBL23477369 0.72
SCHEMBL23477234 0.72
SCHEMBL23178018 0.71 PIK3CD (0.31)
SCHEMBL14591901 0.71 PIK3CD (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9676760-B2 Fused heterocyclic compounds as ion channel modulators GILEAD SCIENCES, INC. (US) 2017-06-13 US disclosed