Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 15/20 | 0.53 |
| ▸ | LMNA | P02545 | 12/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | HTT | P42858 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 11/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19324941 | 0.88 | SMN1; SMN2 (0.51) | MAPTLMNAMEN1KMT2AHTT | |
| SCHEMBL15076378 | 0.86 | MAPT (0.51) | MAPTLMNAMEN1KMT2AHTT | |
| SCHEMBL15076517 | 0.85 | MAPT (0.67) | MAPTLMNAMEN1KMT2AHTT | |
| SCHEMBL21623171 | 0.84 | MAPT (0.53) | MAPTLMNAMEN1KMT2AHTT | |
| SCHEMBL15076530 | 0.83 | MAPT (0.54) | MAPTLMNAMEN1KMT2AHTT | |
| SCHEMBL21623372 | 0.83 | CYP1A2 (0.57) | MAPTLMNAMEN1KMT2AHTT | |
| SCHEMBL21623309 | 0.81 | MAPT (0.59) | MAPTLMNAMEN1KMT2AHTT | |
| SCHEMBL19319385 | 0.80 | SMN1; SMN2 (0.48) | MAPTLMNAMEN1KMT2AHTT | |
| SCHEMBL15076381 | 0.80 | MAPT (0.53) | MAPTLMNAMEN1KMT2AHTT | |
| SCHEMBL21623108 | 0.80 | MAPT (0.57) | MAPTLMNAMEN1KMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9676747-B2 | Hepatitis B antiviral agents | NOVIRA THERAPEUTICS, INC. (US) | 2017-06-13 | — | — | US | disclosed |