Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK10 | P53779 | 1/20 | 0.35 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.35 |
| ▸ | BRAF | P15056 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.30 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.30 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
| ▸ | HTR2B | P41595 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19388112 | 0.88 | BRAF (0.32) | BRAFMAPT | |
| SCHEMBL2705896 | 0.83 | SCN10A (0.36) | BRAFMAPT | |
| SCHEMBL12437141 | 0.82 | TYMS (0.39) | MAPK10BRAFMAPT | |
| SCHEMBL15747146 | 0.82 | TYMS (0.39) | MAPK10RIPK1MAPTCDK5CDK5R1 | |
| SCHEMBL10119929 | 0.79 | KDM4E (0.33) | BRAF | |
| SCHEMBL15113130 | 0.77 | TYMS (0.44) | MAPTCDK5 | |
| SCHEMBL15746227 | 0.77 | MAPT (0.34) | BRAFMAPT | |
| SCHEMBL10141066 | 0.77 | PARP10 (0.36) | MAPTCDK5CDK5R1 | |
| SCHEMBL18467446 | 0.77 | MAPK10 (0.34) | MAPK10RIPK1MAPT | |
| SCHEMBL19521613 | 0.75 | NPSR1 (0.34) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9676802-B2 | Hepatitis C virus inhibitors | ENANTA PHARMACEUTICALS, INC. (US) | 2017-06-13 | — | — | US | disclosed |