SCHEMBL18948619

SCHEMBL18948619

Cc1ccc(-c2ccc3c(c2)C2(c4ccccc4-c4ccccc42)c2cc(-c4ccc(C)c(C(F)(F)F)c4)ccc2-3)cc1C(F)(F)F

nearest known ligand 0.49

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 18/20 0.49
S1PR1 P21453 1/20 0.43
AR P10275 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18947645 0.96 PDK2 (0.46) PDK2S1PR1AR
SCHEMBL29684042 0.89 PDK2 (0.48) PDK2AR
SCHEMBL29683882 0.82 PDK2 (0.46) PDK2
SCHEMBL29756478 0.79 PDK2 (0.50) PDK2
SCHEMBL29512055 0.79 PDK2 (0.50) PDK2
SCHEMBL6297506 0.79 PDK2 (0.50) PDK2
SCHEMBL416947 0.79 PDK2 (0.50) PDK2
SCHEMBL415665 0.79 PDK2 (0.50) PDK2
SCHEMBL29424156 0.79 PDK2 (0.50) PDK2
SCHEMBL10304829 0.77 PDK2 (0.42) PDK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9676906-B1 Polymer of poly(arylene ether)s, manufacturing method thereof and polymer light emitting diode with organic light emitting layer made from the same NATIONAL SUN YAT-SEN UNIVERSITY (TW) 2017-06-13 US disclosed