Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 5/20 | 0.47 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.41 |
| ▸ | AR | P10275 | 4/20 | 0.40 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.39 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.39 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.38 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.37 |
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.35 |
| ▸ | RORC | P51449 | 1/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18947654 | 0.97 | S1PR1 (0.45) | S1PR1NOTUMARPDE3BPDE3A | |
| SCHEMBL18948623 | 0.95 | S1PR1 (0.50) | S1PR1NOTUMARPDE3BPDE3A | |
| SCHEMBL18947655 | 0.93 | S1PR1 (0.47) | S1PR1NOTUMARPDE3BPDE3A | |
| SCHEMBL18948622 | 0.93 | S1PR1 (0.49) | S1PR1NOTUMARPDE3BPDE3A | |
| SCHEMBL18948606 | 0.93 | NOTUM (0.45) | S1PR1NOTUMARPDE3BPDE3A | |
| SCHEMBL18947650 | 0.92 | S1PR1 (0.46) | S1PR1NOTUMARPDE3BPDE3A | |
| SCHEMBL18948633 | 0.90 | S1PR1 (0.45) | S1PR1NOTUMARPDE3BPDE3A | |
| SCHEMBL18947663 | 0.90 | NOTUM (0.43) | S1PR1NOTUMARPDE3BPDE3A | |
| SCHEMBL18948625 | 0.89 | S1PR1 (0.44) | S1PR1NOTUMARPDE3BPDE3A | |
| SCHEMBL18947653 | 0.88 | S1PR1 (0.41) | S1PR1NOTUMARPDE3BPDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9676906-B1 | Polymer of poly(arylene ether)s, manufacturing method thereof and polymer light emitting diode with organic light emitting layer made from the same | NATIONAL SUN YAT-SEN UNIVERSITY (TW) | 2017-06-13 | — | — | US | disclosed |