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SCHEMBL18948746

SCHEMBL18948746

CC1CCCCN(C(=O)CCl)C[C@H](NC(=O)OC(C)(C)C)C(=O)N2C[C@H](OC(=O)N3Cc4cccc(F)c4C3)CC2C(=O)N[C@]2(C(=O)NS(=O)(=O)C3CC3)C[C@@H]12

nearest known ligand 0.41

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ CYP3A4 P08684 2/20 0.33
▸ DDB1 Q16531 1/20 0.30
▸ CRBN Q96SW2 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13435826 0.92 CYP3A4 (0.34) CYP3A4DDB1CRBN
SCHEMBL18948823 0.92 CYP3A4 (0.32) CYP3A4DDB1CRBN
SCHEMBL13415354 0.90 CYP3A4 (0.39) CYP3A4
SCHEMBL13499992 0.90 CYP3A4 (0.39) CYP3A4
SCHEMBL13473713 0.90 CYP3A4 (0.39) CYP3A4
SCHEMBL13474479 0.90 CYP3A4 (0.39) CYP3A4
SCHEMBL18948772 0.89 CYP3A4 (0.31) CYP3A4
SCHEMBL13798461 0.88 CYP3A4 (0.32) CYP3A4DDB1CRBN
SCHEMBL18948771 0.88 CYP3A4 (0.31) CYP3A4
SCHEMBL18948747 0.87 MEN1 (0.32) CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9676785-B2 HCV protease inhibitors and uses thereof CELGENE CAR LLC (BM) 2017-06-13 — — US disclosed
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