Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA1 | P42261 | 3/20 | 0.54 |
| ▸ | PPARA | Q07869 | 4/20 | 0.50 |
| ▸ | CA2 | P00918 | 5/20 | 0.47 |
| ▸ | CA1 | P00915 | 4/20 | 0.47 |
| ▸ | CA12 | O43570 | 2/20 | 0.46 |
| ▸ | CA7 | P43166 | 2/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.46 |
| ▸ | RELA | Q04206 | 4/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10141254 | 0.98 | GRIA1 (0.57) | GRIA1PPARACA2CA1CA12 | |
| SCHEMBL10147477 | 0.94 | CA1 (0.54) | GRIA1PPARACA2CA1CA12 | |
| SCHEMBL19996862 | 0.85 | GRIA1 (0.42) | GRIA1PPARACA2CA1CA12 | |
| SCHEMBL12988696 | 0.85 | CA1 (0.50) | GRIA1PPARACA2CA1CA12 | |
| SCHEMBL14654996 | 0.83 | GRIA1 (0.78) | GRIA1PPARACA2CA1CA12 | |
| SCHEMBL12232575 | 0.82 | GRIA1 (0.57) | GRIA1PPARACA2CA1EPHX1 | |
| SCHEMBL24735803 | 0.81 | GRIA1 (0.83) | GRIA1PPARACA2CA1CA12 | |
| SCHEMBL20734509 | 0.81 | GRIA1 (0.83) | GRIA1PPARACA2CA1CA12 | |
| SCHEMBL13959008 | 0.81 | GRIA1 (0.83) | GRIA1PPARACA2CA1CA12 | |
| SCHEMBL10147425 | 0.81 | GRIA1 (0.50) | GRIA1CA2CA1CA12CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9676802-B2 | Hepatitis C virus inhibitors | ENANTA PHARMACEUTICALS, INC. (US) | 2017-06-13 | — | — | US | disclosed |