Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 20/20 | 0.56 |
| ▸ | ERBB2 | P04626 | 11/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18949484 | 0.94 | EGFR (0.56) | EGFRERBB2 | |
| SCHEMBL18949455 | 0.94 | EGFR (0.64) | EGFRERBB2 | |
| SCHEMBL18949433 | 0.94 | EGFR (0.56) | EGFRERBB2 | |
| SCHEMBL18949445 | 0.92 | EGFR (0.64) | EGFRERBB2 | |
| SCHEMBL18933474 | 0.92 | EGFR (0.64) | EGFRERBB2 | |
| SCHEMBL19389827 | 0.92 | EGFR (0.64) | EGFRERBB2 | |
| SCHEMBL14864913 | 0.91 | EGFR (0.68) | EGFRERBB2 | |
| SCHEMBL18949459 | 0.89 | EGFR (0.56) | EGFRERBB2 | |
| SCHEMBL18933399 | 0.87 | EGFR (0.69) | EGFRERBB2 | |
| SCHEMBL21573267 | 0.87 | EGFR (0.70) | EGFRERBB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9676724-B2 | Cyanoquinoline derivatives | TIANJIN HEMAY ONCOLOGY PHARMACEUTICAL CO., LTD. (CN) | 2017-06-13 | — | — | US | disclosed |