Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 19/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL157722 | 0.90 | NAMPT (0.73) | NAMPT | |
| SCHEMBL160946 | 0.86 | NAMPT (0.72) | NAMPT | |
| SCHEMBL18949505 | 0.84 | NAMPT (0.77) | NAMPT | |
| SCHEMBL18949524 | 0.83 | NAMPT (0.73) | NAMPT | |
| SCHEMBL18949613 | 0.80 | NAMPT (0.69) | NAMPT | |
| SCHEMBL18949502 | 0.79 | NAMPT (0.69) | NAMPTALDH1A1 | |
| SCHEMBL18949579 | 0.79 | NAMPT (0.63) | NAMPT | |
| SCHEMBL166135 | 0.78 | NAMPT (0.82) | NAMPT | |
| SCHEMBL18949496 | 0.78 | NAMPT (0.66) | NAMPT | |
| SCHEMBL18949573 | 0.78 | NAMPT (0.66) | NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9676721-B2 | Compounds and compositions for the inhibition of NAMPT | FORMA TM, LLC (US) | 2017-06-13 | — | — | US | disclosed |