Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 16/20 | 0.67 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18949502 | 0.87 | NAMPT (0.69) | NAMPTALDH1A1 | |
| SCHEMBL160823 | 0.85 | NAMPT (0.73) | NAMPT | |
| SCHEMBL167792 | 0.80 | NAMPT (1.00) | NAMPT | |
| SCHEMBL15373595 | 0.80 | NAMPT (0.76) | NAMPT | |
| SCHEMBL15372323 | 0.80 | NAMPT (0.76) | NAMPT | |
| SCHEMBL18949505 | 0.80 | NAMPT (0.77) | NAMPT | |
| SCHEMBL15373680 | 0.79 | NAMPT (0.77) | NAMPT | |
| SCHEMBL18949588 | 0.77 | NAMPT (0.59) | NAMPT | |
| SCHEMBL15373672 | 0.77 | NAMPT (0.64) | NAMPTALDH1A1 | |
| SCHEMBL18949592 | 0.76 | NAMPT (0.65) | NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9676721-B2 | Compounds and compositions for the inhibition of NAMPT | FORMA TM, LLC (US) | 2017-06-13 | — | — | US | disclosed |