Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTK2 | Q05397 | 20/20 | 0.91 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16130900 | 1.00 | PTK2 (0.91) | PTK2 | |
| SCHEMBL12135104 | 0.95 | PTK2 (1.00) | PTK2 | |
| SCHEMBL12135185 | 0.93 | PTK2 (1.00) | PTK2 | |
| SCHEMBL12135107 | 0.92 | PTK2 (1.00) | PTK2 | |
| SCHEMBL12715035 | 0.90 | PTK2 (0.74) | PTK2 | |
| SCHEMBL12135103 | 0.90 | PTK2 (1.00) | PTK2 | |
| SCHEMBL29381547 | 0.90 | PTK2 (1.00) | PTK2 | |
| SCHEMBL12135109 | 0.89 | PTK2 (1.00) | PTK2 | |
| SCHEMBL18949813 | 0.89 | PTK2 (1.00) | PTK2 | |
| SCHEMBL19918833 | 0.89 | PTK2 (0.89) | PTK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9676762-B2 | Pyrimidine compounds containing seven-membered fused ring systems | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2017-06-13 | — | — | US | disclosed |