Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 5/20 | 0.31 |
| ▸ | CNR1 | P21554 | 4/20 | 0.31 |
| ▸ | CNR2 | P34972 | 3/20 | 0.31 |
| ▸ | ALPL | P05186 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18610303 | 0.94 | CNR1 (0.33) | GPR84CNR1CNR2 | |
| SCHEMBL18411002 | 0.92 | CNR1 (0.32) | GPR84CNR1CNR2 | |
| SCHEMBL19573801 | 0.84 | CNR1 (0.38) | CNR1CNR2 | |
| SCHEMBL19618192 | 0.83 | CNR2 (0.31) | CNR2 | |
| SCHEMBL18431659 | 0.78 | — | — | |
| SCHEMBL22420048 | 0.78 | — | — | |
| SCHEMBL18431565 | 0.78 | — | — | |
| SCHEMBL22420133 | 0.78 | — | — | |
| SCHEMBL21718623 | 0.76 | CNR2 (0.33) | CNR1CNR2 | |
| SCHEMBL25913941 | 0.76 | KCNH2 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9676742-B2 | Process for preparing 4-amino-5-biphenyl-4-yl-2-hydroxymethyl-2-methyl-pentanoic acid compound | THERAVANCE BIOPHARMA R&D IP, LLC (US) | 2017-06-13 | — | — | US | disclosed |