⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21737266 | 0.65 | — | — | |
| SCHEMBL107995 | 0.65 | TSHR (0.38) | — | |
| SCHEMBL107996 | 0.65 | TSHR (0.38) | — | |
| SCHEMBL10129382 | 0.64 | — | — | |
| SCHEMBL27337851 | 0.64 | — | — | |
| SCHEMBL21610569 | 0.62 | — | — | |
| SCHEMBL14065508 | 0.62 | — | — | |
| SCHEMBL21205871 | 0.62 | — | — | |
| SCHEMBL21610534 | 0.62 | — | — | |
| SCHEMBL12958241 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3022208-B1 | METHOD AND APPARATUS FOR THE SYNTHESIS OF DIHYDROARTEMISININ AND ARTEMISININ DERIVATIVES | MAX-PLANCK-GESELLSCHAFT ZUR FÖRDERUNG DER WSS (DE) | 2017-06-14 | — | — | EP | disclosed |