Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 11/20 | 0.37 |
| ▸ | FLT1 | P17948 | 10/20 | 0.37 |
| ▸ | HTR6 | P50406 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NOS1 | P29475 | 3/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.35 |
| ▸ | NOS3 | P29474 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18951966 | 0.84 | KDR (0.33) | KDRFLT1NOS1P2RX7NOS3 | |
| SCHEMBL18939153 | 0.82 | PLAU (0.44) | KDRFLT1 | |
| SCHEMBL18977668 | 0.82 | KDR (0.37) | KDRFLT1HTR6 | |
| Hydrochloric Acid SCHEMBL28648113 | 0.81 | KDR (0.41) | KDRFLT1 | |
| SCHEMBL18939406 | 0.78 | KDR (0.45) | KDRFLT1HTR6P2RX7 | |
| SCHEMBL18977806 | 0.77 | KDR (0.39) | KDRFLT1HTR6P2RX7 | |
| SCHEMBL18960801 | 0.74 | KDR (0.39) | KDRFLT1 | |
| SCHEMBL18952040 | 0.74 | KDR (0.41) | KDRFLT1HTR6 | |
| Hydrochloric Acid SCHEMBL18939070 | 0.74 | KDR (0.39) | KDRFLT1 | |
| SCHEMBL18939006 | 0.74 | PLAU (0.42) | HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108463461-B | Cephem compounds, their preparation and use | 奈加-RGM制药有限公司 | 2021-11-19 | — | — | CN | disclosed |
| EP-3386977-A1 | CEPHEM COMPOUNDS, THEIR PRODUCTION AND USE | NAEJA-RGM Pharmaceuticals ULC (CA) | 2018-10-17 | — | — | EP | disclosed |
| WO-2017096472-A1 | CEPHEM COMPOUNDS, THEIR PRODUCTION AND USE | NAEJA-RGM PHARMACEUTICALS INC. (CA) | 2017-06-15 | — | — | WO | disclosed |