Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT1 | P17948 | 8/20 | 0.44 |
| ▸ | KDR | P35968 | 8/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.44 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.44 |
| ▸ | PLAU | P00749 | 2/20 | 0.43 |
| ▸ | PLG | P00747 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18960794 | 0.84 | FLT1 (0.42) | FLT1KDRHDAC8HDAC6HDAC1 | |
| SCHEMBL18967486 | 0.82 | FLT1 (0.47) | FLT1KDRHDAC8HDAC6HDAC1 | |
| SCHEMBL18952040 | 0.81 | KDR (0.41) | FLT1KDRMAOB | |
| SCHEMBL18952053 | 0.81 | KDR (0.41) | FLT1KDRMAOB | |
| SCHEMBL18939141 | 0.81 | FLT1 (0.54) | FLT1KDRMAOB | |
| SCHEMBL18951992 | 0.80 | KDR (0.45) | FLT1KDRPLAUMAOB | |
| SCHEMBL18939136 | 0.80 | PLAU (0.67) | FLT1KDRHDAC8HDAC6HDAC1 | |
| SCHEMBL18952046 | 0.80 | PLAU (0.49) | FLT1KDRHDAC8HDAC6HDAC1 | |
| Hydrochloric Acid SCHEMBL18939038 | 0.79 | PLAU (0.48) | FLT1KDRHDAC8HDAC6HDAC1 | |
| SCHEMBL30167818 | 0.76 | FLT1 (0.64) | FLT1KDRHDAC8HDAC6HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE48097-E1 | Cephem compounds, their production and use | NAEJA-RGM PHARMACEUTICALS ULC (CA) | 2020-07-14 | — | — | US | disclosed |
| EP-3386977-A1 | CEPHEM COMPOUNDS, THEIR PRODUCTION AND USE | NAEJA-RGM Pharmaceuticals ULC (CA) | 2018-10-17 | — | — | EP | disclosed |
| WO-2017096472-A1 | CEPHEM COMPOUNDS, THEIR PRODUCTION AND USE | NAEJA-RGM PHARMACEUTICALS INC. (CA) | 2017-06-15 | — | — | WO | disclosed |