Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 20/20 | 0.71 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.71 |
| ▸ | SLC22A11 | Q9NSA0 | 1/20 | 0.71 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15165680 | 0.87 | SLC22A12 (0.78) | SLC22A12SLC22A6SLC22A11ABCG2 | |
| SCHEMBL14919143 | 0.84 | SLC22A12 (0.74) | SLC22A12SLC22A6SLC22A11ABCG2 | |
| Verinurad SCHEMBL29362845 | 0.84 | SLC22A12 (1.00) | SLC22A12SLC22A6SLC22A11ABCG2 | |
| SCHEMBL15164011 | 0.84 | SLC22A12 (0.83) | SLC22A12SLC22A6SLC22A11ABCG2 | |
| Verinurad SCHEMBL12070797 | 0.84 | SLC22A12 (1.00) | SLC22A12SLC22A6SLC22A11ABCG2 | |
| Verinurad SCHEMBL21828465 | 0.82 | SLC22A12 (1.00) | SLC22A12SLC22A6SLC22A11ABCG2 | |
| SCHEMBL20020019 | 0.81 | SLC22A12 (0.78) | SLC22A12SLC22A6SLC22A11ABCG2 | |
| Verinurad SCHEMBL18979018 | 0.80 | SLC22A12 (0.88) | SLC22A12SLC22A6SLC22A11ABCG2 | |
| Verinurad SCHEMBL20587211 | 0.80 | SLC22A12 (0.86) | SLC22A12SLC22A6SLC22A11ABCG2 | |
| Verinurad SCHEMBL30109019 | 0.80 | SLC22A12 (0.86) | SLC22A12SLC22A6SLC22A11ABCG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3386485-A1 | PHARMACEUTICAL COMPOSITION COMPRISING A POTENT INHIBITOR OF URAT1 | Ardea Biosciences, Inc. (US) | 2018-10-17 | — | — | EP | disclosed |
| WO-2017097845-A1 | PHARMACEUTICAL COMPOSITION COMPRISING A POTENT INHIBITOR OF URAT1 | ARDEA BIOSCIENCES, INC. (US) | 2017-06-15 | — | — | WO | disclosed |