Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 13/20 | 0.80 |
| ▸ | ACE | P12821 | 5/20 | 0.80 |
| ▸ | MMEL1 | Q495T6 | 3/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17169605 | 1.00 | MME (0.80) | MMEACEMMEL1 | |
| SCHEMBL22556623 | 1.00 | MME (0.80) | MMEACEMMEL1 | |
| Sacubitril SCHEMBL8214132 | 0.91 | MME (0.77) | MMEACEMMEL1 | |
| Sacubitril SCHEMBL1908525 | 0.91 | MME (0.77) | MMEACEMMEL1 | |
| SCHEMBL28456478 | 0.91 | MME (0.77) | MMEACEMMEL1 | |
| Sacubitril SCHEMBL2707112 | 0.91 | MME (0.77) | MMEACEMMEL1 | |
| Sacubitril SCHEMBL18574632 | 0.91 | MME (0.77) | MMEACEMMEL1 | |
| Sacubitril SCHEMBL22420467 | 0.91 | MME (0.77) | MMEACEMMEL1 | |
| Sacubitril SCHEMBL18059569 | 0.91 | MME (0.77) | MMEACEMMEL1 | |
| Sacubitril SCHEMBL18059568 | 0.91 | MME (0.77) | MMEACEMMEL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3386945-A1 | SOLID FORMS OF (2R,4S)-5-(BIPHENYL-4-YL)-4-[(3-CARBOXYPROPIONYL)AMINO]-2- -METHYLPENTANOIC ACID ETHYL ESTER, ITS SALTS AND A PREPARATION METHOD | Zentiva, K.S. (CZ) | 2018-10-17 | — | — | EP | claimed |
| WO-2017097275-A1 | SOLID FORMS OF (2R,4S)-5-(BIPHENYL-4-YL)-4-[(3-CARBOXYPROPIONYL)AMINO]-2- -METHYLPENTANOIC ACID ETHYL ESTER, ITS SALTS AND A PREPARATION METHOD | ZENTIVA, K.S. (CZ) | 2017-06-15 | — | — | WO | claimed |