SCHEMBL18952159

SCHEMBL18952159

NC1(Cc2ccccc2)CC1c1ccccc1.N[C@@]1(Cc2ccccc2)C[C@@H]1c1ccccc1.N[C@]1(Cc2ccccc2)C[C@H]1c1ccccc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
KDM1A O60341 18/20 1.00
MAOA P21397 16/20 1.00
MAOB P27338 16/20 1.00
RCOR1 Q9UKL0 3/20 0.76

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15767610 1.00 KDM1A (1.00) KDM1AMAOAMAOBRCOR1
SCHEMBL15767973 1.00 KDM1A (1.00) KDM1AMAOAMAOBRCOR1
SCHEMBL15767612 1.00 KDM1A (1.00) KDM1AMAOAMAOBRCOR1
SCHEMBL15767315 1.00 KDM1A (1.00) KDM1AMAOAMAOBRCOR1
SCHEMBL15767316 1.00 KDM1A (1.00) KDM1AMAOAMAOBRCOR1
Hydrochloric Acid SCHEMBL15767602 0.98 KDM1A (1.00) KDM1AMAOAMAOBRCOR1
Hydrochloric Acid SCHEMBL15767605 0.98 KDM1A (1.00) KDM1AMAOAMAOBRCOR1
Hydrochloric Acid SCHEMBL15767992 0.98 KDM1A (1.00) KDM1AMAOAMAOBRCOR1
Hydrochloric Acid SCHEMBL15767665 0.98 KDM1A (1.00) KDM1AMAOAMAOBRCOR1
Hydrochloric Acid SCHEMBL15767991 0.98 KDM1A (1.00) KDM1AMAOAMAOBRCOR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2017097865-A9 COMBINATION OF CALORIC RESTRICTION (CR) OR IGF1/INSULIN RECEPTOR INHIBITOR WITH LSD1 INHIBITOR ISTITUTO EUROPEO DI ONCOLOGIA (IT) 2017-08-31 WO disclosed
WO-2017097865-A1 COMBINATION OF CALORIC RESTRICTION (CR) OR IGF1/INSULIN RECEPTOR INHIBITOR WITH LSD1 INHIBITOR ISTITUTO EUROPEO DI ONCOLOGIA (IT) 2017-06-15 WO disclosed