Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 16/20 | 1.00 |
| ▸ | CA2 | P00918 | 16/20 | 1.00 |
| ▸ | CA9 | Q16790 | 16/20 | 1.00 |
| ▸ | CA12 | O43570 | 13/20 | 1.00 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.64 |
| ▸ | CASP3 | P42574 | 3/20 | 0.60 |
| ▸ | CASP7 | P55210 | 3/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18955434 | 0.88 | CA12 (0.78) | CA1CA2CA9CA12CHRM5 | |
| SCHEMBL18955436 | 0.87 | CA12 (0.77) | CA1CA2CA9CA12CHRM5 | |
| SCHEMBL18954543 | 0.86 | CA1 (0.79) | CA1CA2CA9CA12 | |
| SCHEMBL18954905 | 0.86 | CA1 (0.79) | CA1CA2CA9CA12 | |
| SCHEMBL18954728 | 0.85 | CA1 (1.00) | CA1CA2CA9CA12 | |
| SCHEMBL18954788 | 0.84 | CA1 (0.79) | CA1CA2CA9CA12 | |
| SCHEMBL18954733 | 0.83 | CA1 (0.77) | CA1CA2CA9CA12 | |
| SCHEMBL18954798 | 0.83 | CA1 (0.78) | CA1CA2CA9CA12 | |
| SCHEMBL18954924 | 0.81 | CA1 (1.00) | CA1CA2CA9CA12 | |
| SCHEMBL4735891 | 0.81 | CHRM5 (0.68) | CA1CA2CA9CA12CHRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017099695-A1 | N-[(AMINOSULFONYL)PHENYL]-2-(1,2-DIHYDRO-2-OXO-3H-INDOL-3-YLIDENE)-HYDRAZINECARBOTHIOAMIDE DERIVATIVES FOR TREATING CANCER AND IMMUNOLOGICAL DISORDERS | ISTANBUL UNIVERSITESI REKTORLUGU (TR) | 2017-06-15 | — | — | WO | disclosed |