Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.67 |
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.54 |
| ▸ | ACHE | P22303 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | CES2 | O00748 | 1/20 | 0.48 |
| ▸ | CES1 | P23141 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30833623 | 1.00 | TSHR (0.67) | TSHRLMNACYP1A2CYP2D6CYP2C9 | |
| SCHEMBL2928940 | 0.89 | TSHR (0.54) | TSHRLMNACYP1A2CYP2D6CYP2C9 | |
| Dinitrophenylene SCHEMBL27831167 | 0.89 | TSHR (0.63) | TSHRLMNACYP1A2CYP2D6CYP2C9 | |
| Formic Acid Methyl Ester SCHEMBL28356814 | 0.88 | CYP2C19 (0.55) | TSHRLMNACYP1A2CYP2D6CYP2C9 | |
| SCHEMBL28638417 | 0.86 | TSHR (0.51) | TSHRLMNACYP1A2CYP2D6CYP2C9 | |
| SCHEMBL18347106 | 0.85 | TSHR (0.62) | TSHRLMNACYP1A2CYP2D6CYP2C9 | |
| SCHEMBL850312 | 0.85 | TSHR (0.62) | TSHRLMNACYP1A2CYP2D6CYP2C9 | |
| SCHEMBL29531585 | 0.85 | TSHR (0.62) | TSHRLMNACYP1A2CYP2D6CYP2C9 | |
| SCHEMBL10918542 | 0.83 | TSHR (0.71) | TSHRLMNACYP1A2CYP2D6CYP2C9 | |
| Bromide SCHEMBL20258220 | 0.83 | TSHR (0.61) | TSHRLMNACYP1A2CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 2231 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116375643-B | Deaconitine derivative and preparation method and application thereof | 中国人民解放军海军军医大学 | 2025-04-01 | — | — | CN | claimed |
| CN-119569808-A | Method for modifying C-21 position structure of fusidic acid | 浙江工业大学 | 2025-03-07 | — | — | CN | claimed |
| CN-118554122-A | PI nanofiber composite membrane with lithium dendrite inhibition function and preparation and application thereof | 河北科技大学 | 2024-08-27 | — | — | CN | claimed |
| CN-116496335-B | Modified nucleotide and application thereof | 中国药科大学 | 2024-03-08 | — | — | CN | claimed |
| CN-116496335-A | Modified nucleotide and application thereof | 中国药科大学 | 2023-07-28 | — | — | CN | claimed |
| CN-116375643-A | Deaconitine derivative and preparation method and application thereof | 中国人民解放军海军军医大学 | 2023-07-04 | — | — | CN | claimed |
| CN-111004228-B | GSK-3 beta/ChE double inhibitor and preparation method and application thereof | 中国药科大学 | 2023-05-23 | — | — | CN | claimed |
| US-20210214372-A1 | SMALL MOLECULE ANTAGONIST COMPOUND TAC5 SERIES HAVING TOLL-LIKE RECEPTOR 3/7/8/9 INHIBITORY FUNCTION | AJOU UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION (KR) | 2021-07-15 | — | — | US | claimed |
| WO-2021047572-A1 | GSK-3β/CHE DOUBLE INHIBITOR, PREPARATION METHOD THEREFOR AND USE THEREOF | 中国药科大学 | 2021-03-18 | — | — | WO | claimed |
| CN-112110908-A | 1, 3-disubstituted indazole compound and preparation method and application thereof | 山东大学 | 2020-12-22 | — | — | CN | claimed |
| CN-105218397-B | Method for synthesizing 2-azidomethyl-4-nitrobenzoyl chloride | 济南大学 | 2017-05-10 | — | — | CN | claimed |
| CN-103626705-B | 1 (3 benzamido benzyl) 1H indazole 3 Carbox amide and preparation method thereof and anti-viral uses | 中国科学院上海药物研究所 | 2016-12-21 | — | — | CN | claimed |
| CN-105017569-A | Degradable composite tourist commodity packaging film and preparation method thereof | JILIN TECHNOLOGY COLLEGE OF ELECTRONIC INFORMATION | 2015-11-04 | — | — | CN | claimed |
| CN-102219800-B | Organic substituted boric acid ester, boron affinity functional material using organic substituted boric acid ester as functional monomer as well as preparation and application of organic substituted boric acid ester | NANJING UNIVERSITY OF TECHNOLOGY | 2015-02-25 | — | — | CN | claimed |
| CN-104370936-A | Novel pyruvate kinase M2 activator and its synthetic method | SUZHOU VIVOTIDE BIOTECHNOLOGIES CO LTD | 2015-02-25 | — | — | CN | claimed |
| CN-102219800-A | Organic substituted boric acid ester, boron affinity functional material using organic substituted boric acid ester as functional monomer as well as preparation and application of organic substituted boric acid ester | NANJING UNIVERSITY OF TECHNOLOGY | 2011-10-19 | — | — | CN | claimed |
| US-7777069-B2 | Prodrugs of carbamate inhibitors of IMPDH | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2010-08-17 | — | — | US | claimed |
| US-20090093639-A1 | Prodrugs of carbamate inhibitors of IMPDH | VERTEX PHARMACEUTICAL INCORPORATED (US) | 2009-04-09 | — | — | US | claimed |
| EP-1754705-A2 | Antagonists for treatment of CD11/CD18 adhesion receptor mediated disorders | Genentech, Inc. (US) | 2007-02-21 | — | — | EP | claimed |
| US-4257915-A | USE IN PHOTOPOLYMERIZATION OF ETHYLENICALLY UNSATURATED MONOMERS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1981-03-24 | — | — | US | claimed |