Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SAE1 | Q9UBE0 | 20/20 | 0.56 |
| ▸ | UBA2 | Q9UBT2 | 20/20 | 0.56 |
| ▸ | NAE1 | Q13564 | 16/20 | 0.56 |
| ▸ | UBA3 | Q8TBC4 | 16/20 | 0.56 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18962831 | 0.91 | SAE1 (0.46) | SAE1UBA2NAE1UBA3 | |
| SCHEMBL18962835 | 0.91 | SAE1 (0.46) | SAE1UBA2NAE1UBA3 | |
| SCHEMBL17398707 | 0.88 | SAE1 (0.56) | SAE1UBA2NAE1UBA3CA1 | |
| SCHEMBL17398705 | 0.87 | SAE1 (0.63) | SAE1UBA2NAE1UBA3CA1 | |
| SCHEMBL31371846 | 0.84 | SAE1 (0.80) | SAE1UBA2NAE1UBA3CA1 | |
| SCHEMBL17398607 | 0.84 | SAE1 (0.80) | SAE1UBA2NAE1UBA3CA1 | |
| SCHEMBL17398609 | 0.84 | SAE1 (0.80) | SAE1UBA2NAE1UBA3CA1 | |
| SCHEMBL17398379 | 0.84 | SAE1 (0.80) | SAE1UBA2NAE1UBA3CA1 | |
| SCHEMBL31372192 | 0.84 | SAE1 (0.80) | SAE1UBA2NAE1UBA3CA1 | |
| SCHEMBL18962805 | 0.82 | SAE1 (0.56) | SAE1UBA2NAE1UBA3CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9683003-B2 | Heteroaryl compounds useful as inhibitors of SUMO activating enzyme | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2017-06-20 | — | — | US | claimed |