Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNK3 | O14649 | 16/20 | 0.67 |
| ▸ | KCNK9 | Q9NPC2 | 16/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18952499 | 0.88 | GAA (0.65) | KCNK3KCNK9KDM4EGAASLC2A1 | |
| SCHEMBL18963197 | 0.86 | KDM4E (0.75) | KCNK3KCNK9KDM4EGAASLC2A1 | |
| SCHEMBL22635913 | 0.86 | KCNK3 (0.66) | KCNK3KCNK9KDM4EGAASLC2A1 | |
| SCHEMBL22269546 | 0.86 | KCNK3 (0.66) | KCNK3KCNK9KDM4EGAASLC2A1 | |
| SCHEMBL18963147 | 0.86 | KCNK3 (0.65) | KCNK3KCNK9KDM4EGAASLC2A1 | |
| SCHEMBL22269545 | 0.86 | KCNK3 (0.66) | KCNK3KCNK9KDM4EGAASLC2A1 | |
| Hydrochloric Acid SCHEMBL18952385 | 0.85 | KCNK3 (0.64) | KCNK3KCNK9KDM4EGAASLC2A1 | |
| SCHEMBL21904739 | 0.84 | KDM4E (0.63) | KCNK3KCNK9KDM4EGAASLC2A1 | |
| SCHEMBL22269606 | 0.83 | KCNK3 (0.67) | KCNK3KCNK9KDM4EGAASLC2A1 | |
| SCHEMBL22269533 | 0.83 | KCNK3 (0.67) | KCNK3KCNK9KDM4EGAASLC2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3386979-B1 | 2-PHENYL-3-(PIPERAZINOMETHYL)IMIDAZO[1,2-A]PYRIDINE DERIVATIVES AS BLOCKERS OF THE TASK-1 AND TASK-2 CHANNELS FOR TREATING SLEEP-RELATED BREATHING DISORDERS | Bayer Pharma AG (DE) | 2020-07-29 | — | — | EP | disclosed |
| WO-2017097792-A1 | 2-PHENYL-3-(PIPERAZINOMETHYL)IMIDAZO[1,2-A]PYRIDINE DERIVATIVES AS BLOCKERS OF TASK-1 AND TASK-2 CHANNELS, FOR THE TREATMENT OF SLEEP-RELATED BREATHING DISORDERS | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2017-06-15 | — | — | WO | disclosed |