Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 10/20 | 0.37 |
| ▸ | DDB1 | Q16531 | 4/20 | 0.37 |
| ▸ | SMYD3 | Q9H7B4 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13320617 | 0.81 | CRBN (0.40) | CRBNDDB1SMYD3 | |
| SCHEMBL2845902 | 0.81 | CRBN (0.40) | CRBNDDB1SMYD3 | |
| SCHEMBL19143188 | 0.81 | CRBN (0.40) | CRBNDDB1SMYD3 | |
| SCHEMBL19143405 | 0.79 | CRBN (0.41) | CRBNDDB1SMYD3 | |
| SCHEMBL725492 | 0.67 | CRBN (0.51) | CRBN | |
| SCHEMBL29799872 | 0.67 | CRBN (0.51) | CRBN | |
| Bromide SCHEMBL4113407 | 0.66 | CRBN (0.50) | CRBN | |
| SCHEMBL1092914 | 0.65 | CRBN (0.43) | CRBNDDB1 | |
| SCHEMBL23101608 | 0.64 | TP53 (0.38) | — | |
| SCHEMBL29381060 | 0.64 | TP53 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2054422-B1 | ACRYLAMIDE DERIVATIVES AS FAB I INHIBITORS | DEBIOPHARM INT SA (CH) | 2017-06-14 | — | — | EP | disclosed |