Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 2/20 | 0.49 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.49 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.49 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.45 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.45 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | PLG | P00747 | 1/20 | 0.42 |
| ▸ | PLAU | P00749 | 1/20 | 0.42 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.42 |
| ▸ | KLK1 | P06870 | 1/20 | 0.42 |
| ▸ | SIRT2 | Q8IXJ6 | 11/20 | 0.42 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.41 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 2/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22061206 | 0.90 | PLAU (0.47) | PRSS1PRSS2PRSS3HSD17B1HSD17B2 | |
| SCHEMBL24030873 | 0.90 | PLAU (0.49) | PRSS1PRSS2PRSS3F2PLG | |
| SCHEMBL24031192 | 0.90 | PLAU (0.47) | PRSS1PRSS2PRSS3HSD17B1HSD17B2 | |
| SCHEMBL25654291 | 0.89 | PLAU (0.50) | PRSS1PRSS2PRSS3HSD17B1HSD17B2 | |
| SCHEMBL23946738 | 0.88 | PLAU (0.53) | PRSS1HSD17B1HSD17B2F2PLG | |
| SCHEMBL21707251 | 0.88 | PLAU (0.53) | PRSS1PRSS2PRSS3F2PLG | |
| SCHEMBL21707252 | 0.88 | PRSS1 (0.59) | PRSS1PRSS2PRSS3F2PLG | |
| SCHEMBL15004143 | 0.88 | PRSS1 (0.62) | PRSS1PRSS2PRSS3F2PLG | |
| SCHEMBL25008241 | 0.87 | ESR1 (0.46) | PRSS1PRSS2PRSS3F2PLG | |
| SCHEMBL23654435 | 0.86 | PLAU (0.58) | PRSS1F2PLGPLAUKLKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3386987-B1 | ORGANIC ELECTROLUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME | ROHM & HAAS ELECT MATERIALS KOREA LTD (KR) | 2020-04-15 | — | — | EP | disclosed |
| WO-2017099360-A1 | ORGANIC ELECTROLUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME | ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) | 2017-06-15 | — | — | WO | disclosed |