Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 14/20 | 0.96 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.66 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | FAAH | O00519 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | CPT2 | P23786 | 1/20 | 0.50 |
| ▸ | CPT1A | P50416 | 1/20 | 0.50 |
| ▸ | CPT1B | Q92523 | 1/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25834895 | 0.98 | EPHX1 (1.00) | EPHX1SMN1; SMN2MEN1FAAHMAPK1 | |
| SCHEMBL27052608 | 0.98 | EPHX1 (1.00) | EPHX1SMN1; SMN2MEN1FAAHMAPK1 | |
| SCHEMBL9784658 | 0.98 | EPHX1 (1.00) | EPHX1SMN1; SMN2MEN1FAAHMAPK1 | |
| SCHEMBL12196042 | 0.98 | EPHX1 (1.00) | EPHX1SMN1; SMN2MEN1FAAHMAPK1 | |
| SCHEMBL13777205 | 0.98 | EPHX1 (1.00) | EPHX1SMN1; SMN2MEN1FAAHMAPK1 | |
| SCHEMBL8394872 | 0.94 | EPHX1 (0.85) | EPHX1SMN1; SMN2MEN1FAAHMAPK1 | |
| SCHEMBL20953587 | 0.91 | EPHX1 (0.80) | EPHX1SMN1; SMN2MEN1MAPK1KMT2A | |
| SCHEMBL23560680 | 0.86 | EPHX1 (0.72) | EPHX1SMN1; SMN2MEN1KMT2AEPHX2 | |
| SCHEMBL2625542 | 0.85 | EPHX1 (0.70) | EPHX1SMN1; SMN2MEN1FAAHMAPK1 | |
| SCHEMBL15700937 | 0.84 | EPHX1 (0.70) | EPHX1SMN1; SMN2CPT2CPT1ACPT1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1411929-B1 | MALONYL-COA DECARBOXYLASE INHIBITORS USEFUL AS METABOLIC MODULATORS | CHUGAI PHARMACEUTICAL CO LTD (JP) | 2011-05-11 | — | — | EP | claimed |