Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.73 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.73 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.73 |
| ▸ | TSHR | P16473 | 1/20 | 0.73 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.73 |
| ▸ | FAAH | O00519 | 4/20 | 0.70 |
| ▸ | DGKA | P23743 | 1/20 | 0.65 |
| ▸ | PGR | P06401 | 2/20 | 0.62 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.62 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.62 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.62 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.62 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.61 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.61 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.61 |
| ▸ | PRKCA | P17252 | 1/20 | 0.61 |
| ▸ | TERT | O14746 | 3/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.61 |
| ▸ | MAPT | P10636 | 2/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7557819 | 1.00 | HSD17B10 (0.73) | HSD17B10CYP3A4ALOX15ALDH1A1TSHR | |
| SCHEMBL6853542 | 1.00 | HSD17B10 (0.73) | HSD17B10CYP3A4ALOX15ALDH1A1TSHR | |
| SCHEMBL119944 | 1.00 | HSD17B10 (0.73) | HSD17B10CYP3A4ALOX15ALDH1A1TSHR | |
| SCHEMBL588561 | 1.00 | HSD17B10 (0.73) | HSD17B10CYP3A4ALOX15ALDH1A1TSHR | |
| Ethyl Oleate SCHEMBL2798 | 1.00 | HSD17B10 (0.73) | HSD17B10CYP3A4ALOX15ALDH1A1TSHR | |
| SCHEMBL3847096 | 1.00 | HSD17B10 (0.73) | HSD17B10CYP3A4ALOX15ALDH1A1TSHR | |
| SCHEMBL25490302 | 1.00 | HSD17B10 (0.73) | HSD17B10CYP3A4ALOX15ALDH1A1TSHR | |
| SCHEMBL588560 | 1.00 | HSD17B10 (0.73) | HSD17B10CYP3A4ALOX15ALDH1A1TSHR | |
| SCHEMBL12842074 | 1.00 | HSD17B10 (0.73) | HSD17B10CYP3A4ALOX15ALDH1A1TSHR | |
| SCHEMBL546545 | 1.00 | HSD17B10 (0.73) | HSD17B10CYP3A4ALOX15ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2493474-A2 | METHODS AND COMPOSITIONS FOR SUSTAINED DELIVERY OF DRUGS | Intratus, Inc. (US) | 2012-09-05 | — | — | EP | disclosed |
| WO-2011053792-A2 | METHODS AND COMPOSITIONS FOR SUSTAINED DELIVERY OF DRUGS | INTRATUS, INC. (US) | 2011-05-05 | — | — | WO | disclosed |