Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PADI4 | Q9UM07 | 20/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29850728 | 0.91 | PADI4 (0.73) | PADI4 | |
| SCHEMBL18969393 | 0.91 | PADI4 (0.73) | PADI4 | |
| SCHEMBL18968555 | 0.91 | PADI4 (0.58) | PADI4 | |
| SCHEMBL18968803 | 0.88 | PADI4 (0.67) | PADI4 | |
| SCHEMBL18940650 | 0.88 | PADI4 (0.76) | PADI4 | |
| SCHEMBL23435968 | 0.85 | PADI4 (0.57) | PADI4 | |
| SCHEMBL18968862 | 0.85 | PADI4 (0.57) | PADI4 | |
| SCHEMBL18969428 | 0.85 | PADI4 (0.57) | PADI4 | |
| SCHEMBL23436002 | 0.85 | PADI4 (0.69) | PADI4 | |
| SCHEMBL23435550 | 0.85 | PADI4 (0.70) | PADI4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3885342-A1 | BICYCLIC INHIBITORS OF PAD4 | Padlock Therapeutics, Inc. (US) | 2021-09-29 | — | — | EP | disclosed |
| EP-3386590-B1 | BICYCLIC INHIBITORS OF PAD4 | PADLOCK THERAPEUTICS INC (US) | 2021-06-02 | — | — | EP | disclosed |
| WO-2017100594-A1 | BICYCLIC INHIBITORS OF PAD4 | PADLOCK THERAPEUTICS, INC. (US) | 2017-06-15 | — | — | WO | disclosed |