Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | TLR2 | O60603 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18738984 | 0.93 | MEN1 (0.47) | MEN1KMT2ARECQLKDM4ECYP1A2 | |
| SCHEMBL25851515 | 0.92 | MEN1 (0.47) | MEN1KMT2ARECQLKDM4ECYP1A2 | |
| SCHEMBL25885013 | 0.92 | MEN1 (0.52) | MEN1KMT2ARECQLKDM4ECYP1A2 | |
| SCHEMBL24379925 | 0.92 | MEN1 (0.50) | MEN1KMT2ARECQLKDM4ECYP1A2 | |
| SCHEMBL23806133 | 0.92 | MEN1 (0.50) | MEN1KMT2ARECQLKDM4ECYP1A2 | |
| SCHEMBL22014884 | 0.92 | MEN1 (0.50) | MEN1KMT2ARECQLKDM4ECYP1A2 | |
| SCHEMBL25466890 | 0.92 | MEN1 (0.50) | MEN1KMT2ARECQLKDM4ECYP1A2 | |
| SCHEMBL18908647 | 0.92 | MEN1 (0.50) | MEN1KMT2ARECQLKDM4ECYP1A2 | |
| SCHEMBL25600684 | 0.83 | KMT2A (0.53) | MEN1KMT2ARECQLEPHX2CYP2D6 | |
| SCHEMBL25729590 | 0.81 | KMT2A (0.43) | MEN1KMT2ARECQLEPHX2TLR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9994855-B2 | Compositions and methods for modulating growth hormone receptor expression | IONIS PHARMACEUTICALS, INC. (US) | 2018-06-12 | — | — | US | disclosed |
| US-20170166899-A1 | COMPOSITIONS AND METHODS FOR MODULATING GROWTH HORMONE RECEPTOR EXPRESSION | IONIS PHARMACEUTICALS, INC. (US) | 2017-06-15 | — | — | US | disclosed |