Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 19/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL519251 | 0.85 | PDE10A (0.71) | PDE10A | |
| SCHEMBL16162029 | 0.71 | PDE10A (0.71) | PDE10A | |
| SCHEMBL525174 | 0.71 | PDE10A (0.75) | PDE10A | |
| SCHEMBL10259043 | 0.70 | PDE10A (0.75) | PDE10A | |
| SCHEMBL16161901 | 0.69 | PDE10A (0.57) | PDE10A | |
| SCHEMBL519437 | 0.68 | PDE10A (0.72) | PDE10A | |
| SCHEMBL3505539 | 0.67 | PDE10A (0.62) | PDE10A | |
| SCHEMBL519367 | 0.67 | PDE10A (0.54) | PDE10A | |
| SCHEMBL519123 | 0.67 | PDE10A (1.00) | PDE10A | |
| SCHEMBL10267055 | 0.67 | PDE10A (0.54) | PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2602254-B1 | HETEROCYCLIC COMPOUND | TAKEDA PHARMACEUTICALS CO (JP) | 2017-06-14 | — | — | EP | disclosed |