Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTN3A1 | O00481 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ELANE | P08246 | 2/20 | 0.41 |
| ▸ | PRTN3 | P24158 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | MYC | P01106 | 1/20 | 0.39 |
| ▸ | MAX | P61244 | 1/20 | 0.39 |
| ▸ | CTSV | O60911 | 3/20 | 0.38 |
| ▸ | CTSL | P07711 | 3/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | KLK1 | P06870 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18973569 | 0.89 | BTN3A1 (0.46) | BTN3A1MAPTMEN1KMT2AELANE | |
| SCHEMBL18973574 | 0.89 | BTN3A1 (0.46) | BTN3A1MAPTMEN1KMT2AELANE | |
| SCHEMBL18973470 | 0.88 | BTN3A1 (0.49) | BTN3A1MAPTMEN1KMT2AELANE | |
| SCHEMBL18973682 | 0.86 | BTN3A1 (0.44) | BTN3A1MAPTMEN1KMT2AELANE | |
| SCHEMBL22081623 | 0.86 | BTN3A1 (0.46) | BTN3A1MAPTMEN1KMT2ANPC1 | |
| SCHEMBL18973570 | 0.86 | BTN3A1 (0.49) | BTN3A1ELANEPRTN3KLK1 | |
| SCHEMBL18973565 | 0.85 | BTN3A1 (0.48) | BTN3A1ELANEPRTN3KLK1 | |
| SCHEMBL22065158 | 0.85 | BTN3A1 (0.48) | BTN3A1ELANEPRTN3ALDH1A1KLK1 | |
| SCHEMBL18973564 | 0.83 | BTN3A1 (0.55) | BTN3A1MEN1KMT2AELANEPRTN3 | |
| SCHEMBL18973469 | 0.82 | BTN3A1 (0.49) | BTN3A1MEN1KMT2AELANEPRTN3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017098252-A1 | DIASTEREOSELECTIVE SYNTHESIS OF PHOSPHATE DERIVATIVES AND OF THE GEMCITABINE PRODRUG NUC-1031 | NUCANA BIOMED LIMITED (GB) | 2017-06-15 | — | — | WO | disclosed |