Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1982314 | 0.87 | MAPK1 (0.65) | MAPK1KDM4EALDH1A1TDP1 | |
| SCHEMBL14901116 | 0.78 | MAPK1 (0.54) | MAPK1KDM4EALDH1A1TDP1 | |
| SCHEMBL14901115 | 0.78 | MAPK1 (0.54) | MAPK1KDM4EALDH1A1TDP1 | |
| Terbuprol SCHEMBL16001415 | 0.78 | MAPK1 (0.54) | MAPK1KDM4EALDH1A1TDP1 | |
| Terbuprol SCHEMBL1815375 | 0.78 | MAPK1 (0.54) | MAPK1KDM4EALDH1A1TDP1 | |
| SCHEMBL5474358 | 0.78 | MAPK1 (0.54) | MAPK1KDM4EALDH1A1TDP1 | |
| Terbuprol SCHEMBL16001420 | 0.78 | MAPK1 (0.54) | MAPK1KDM4EALDH1A1TDP1 | |
| SCHEMBL9309371 | 0.77 | MAPK1 (0.59) | MAPK1KDM4EALDH1A1TDP1 | |
| SCHEMBL14901102 | 0.75 | MAPK1 (0.56) | MAPK1KDM4EALDH1A1TDP1 | |
| SCHEMBL116799 | 0.75 | MAPK1 (0.56) | MAPK1KDM4EALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2521707-B1 | BISPHENOL DERIVATIVES AND THEIR USE AS ANDROGEN RECEPTOR ACTIVITY MODULATORS | BRITISH COLUMBIA CANCER AGENCY BRANCH (CA) | 2017-06-14 | — | — | EP | disclosed |