Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.68 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.51 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.51 |
| ▸ | DRD2 | P14416 | 5/20 | 0.47 |
| ▸ | SLC5A7 | Q9GZV3 | 1/20 | 0.43 |
| ▸ | PARP1 | P09874 | 2/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1891613 | 0.91 | HRH3 (0.57) | HRH3CARM1PRMT6PARP1MAOA | |
| SCHEMBL5657345 | 0.87 | HRH3 (0.68) | HRH3CARM1PRMT6DRD2 | |
| SCHEMBL1896242 | 0.84 | HRH3 (0.49) | HRH3CARM1PRMT6DRD2PARP1 | |
| SCHEMBL20328148 | 0.84 | CARM1 (0.70) | HRH3CARM1PRMT6DRD2SLC5A7 | |
| SCHEMBL20217556 | 0.83 | HRH3 (0.69) | HRH3CARM1PRMT6DRD2PARP1 | |
| SCHEMBL1899977 | 0.82 | HRH3 (0.47) | HRH3CARM1PRMT6 | |
| SCHEMBL188648 | 0.82 | HRH3 (0.63) | HRH3CARM1PRMT6MAOAMAOB | |
| SCHEMBL5206619 | 0.81 | HRH3 (1.00) | HRH3MAOAMAOB | |
| SCHEMBL19207211 | 0.78 | HRH3 (0.52) | HRH3CARM1PRMT6DRD2 | |
| SCHEMBL189065 | 0.77 | HRH3 (0.53) | HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2493571-A1 | ALKYNYL DERIVATIVES USEFUL AS DPP-1 INHIBITORS | Janssen Pharmaceutica, N.V. (BE) | 2012-09-05 | — | — | EP | disclosed |
| WO-2011059731-A1 | ALKYNYL DERIVATIVES USEFUL AS DPP-1 INHIBITORS | JANSSEN PHARMACEUTICA NV (BE) | 2011-05-19 | — | — | WO | disclosed |