SCHEMBL1897515

SCHEMBL1897515

O=C(O)C=CCC(O)CO

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.42
LMNA P02545 3/20 0.42
GABRR1 P24046 2/20 0.42
GABRR2 P28476 2/20 0.42
BLM P54132 2/20 0.42
GABRR3 A8MPY1 1/20 0.42
APEX1 P27695 1/20 0.42
NPSR1 Q6W5P4 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
TP53 P04637 1/20 0.36
EGLN1 Q9GZT9 1/20 0.36
EGLN3 Q9H6Z9 1/20 0.36
ALDH1A1 P00352 1/20 0.36
OR51E2 Q9H255 1/20 0.35
SLC22A6 Q4U2R8 1/20 0.31
THRB P10828 1/20 0.31
GABRP O00591 2/20 0.30
GABRD O14764 2/20 0.30
GABRA1 P14867 2/20 0.30
GABRB1 P18505 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5973011 1.00 TSHR (0.42) TSHRLMNAGABRR1GABRR2BLM
SCHEMBL10575377 1.00 TSHR (0.42) TSHRLMNAGABRR1GABRR2BLM
SCHEMBL10575391 1.00 TSHR (0.42) TSHRLMNAGABRR1GABRR2BLM
SCHEMBL8823395 0.87 TSHR (0.48) TSHRLMNAGABRR1GABRR2BLM
SCHEMBL8823392 0.87 TSHR (0.48) TSHRLMNAGABRR1GABRR2BLM
SCHEMBL22955550 0.82 TSHR (0.39) TSHRLMNAGABRR1GABRR2BLM
Fumaric Acid SCHEMBL4439688 0.79 TSHR (0.53) TSHRLMNAGABRR1GABRR2BLM
Fumaric Acid SCHEMBL15689550 0.79 TSHR (0.53) TSHRLMNAGABRR1GABRR2BLM
Maleic Acid SCHEMBL29021089 0.79 TSHR (0.53) TSHRLMNAGABRR1GABRR2BLM
Fumaric Acid SCHEMBL19347274 0.79 TSHR (0.53) TSHRLMNAGABRR1GABRR2BLM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 124 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2017012963-A1 POLYMERIZABLE FATTY ACID-DERIVATIVE-MONOMERS WITH TERMINAL OLEFINIC DOUBLE BONDS, POLYMERS CONTAINING SAME MONOMERS, PRODUCTION AND USE THEREOF BASF SE (DE) 2017-01-26 WO claimed
CN-100548455-C The composite that comprises layered hydrophilic coatings UNIV MCMASTER (CA) 2009-10-14 CN claimed
EP-1084694-B2 Cosmetic composition containing at least a silicone/acrylate copolymer and at least a conditioning agent OREAL (FR) 2008-12-17 EP claimed
EP-1084695-B1 Cosmetic composition containing at least a silicone/acrylate copolymer and at least a non-cellulosic thickening agent OREAL (FR) 2008-11-05 EP claimed
EP-1114074-B1 POLYMERIZABLE MATERIAL AND SHEET MATERIAL DERIVED THEREFROM POLYBIOMED LTD (GB) 2007-10-10 EP claimed
CN-101048222-A Composite material comprising layered hydrophilic coatings UNIV MCMASTER (CA) 2007-10-03 CN claimed
EP-1084697-B1 Cosmetic composition containing at least a silicone/acrylate copolymer and at least a vinyllactame non-ionic polymer OREAL (FR) 2004-02-04 EP claimed
EP-1084694-B1 Cosmetic composition containing at least a silicone/acrylate copolymer and at least a conditioning agent OREAL (FR) 2003-12-03 EP claimed
EP-1084698-B1 Cosmetic composition containing at least a silicone/acrylate copolymer and at least a silicone graft copolymer OREAL (FR) 2003-07-09 EP claimed
WO-2024043326-A1 HYDROPHILIC OIL REPELLENT POLYMER 住友化学株式会社 2024-02-29 WO disclosed
CN-111683978-B Polymer, resin composition, molded article, and method for producing polymer 住友化学株式会社 2023-06-13 CN disclosed
CN-111303789-B Anti-static wafer cutting protective film and preparation method thereof 广东硕成科技有限公司 2021-12-31 CN disclosed
CN-111378169-A Force-induced response hybrid crosslinked dynamic polymer 翁秋梅 2020-07-07 CN disclosed
CN-111303789-A Anti-static wafer cutting protective film and preparation method thereof 广东硕成科技有限公司 2020-06-19 CN disclosed
EP-0605677-A1 SILICON OR SILICA SUBSTRATE WITH A MODIFIED SURFACE AND PROCESS FOR PRODUCING THE SAME OWENS CORNING (US) 1994-07-13 EP disclosed
WO-1994002425-A2 SILICON OR SILICA SUBSTRATE WITH A MODIFIED SURFACE, PROCESS FOR PRODUCING THE SAME, NEW ORTHOESTERS AND PROCESS FOR PRODUCING THE SAME GURIT-ESSEX AG (CH) 1994-02-03 WO disclosed
EP-0183132-B1 A PROCESS FOR THE PREPARATION OF HMG-COA REDUCTASE INHIBITORS AND INTERMEDIATE COMPOUNDS EMPLOYED THEREIN MERCK FROSST CANADA INC. (CA) 1989-10-18 EP disclosed
US-4855481-A Process for the preparation of HMG-CoA reductase inhibitors and intermediate compounds employed therein MERCK FROSST CANADA, INC. (CA) 1989-08-08 US disclosed
US-4611068-A Process for the preparation of HMG-CoA reductase inhibitors and intermediate compounds employed therein MERCK FROSST CANADA, INC. (CA) 1986-09-09 US disclosed
EP-0183132-A2 A process for the preparation of HMG-CoA reductase inhibitors and intermediate compounds employed therein MERCK FROSST CANADA INC. (CA) 1986-06-04 EP disclosed