Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PADI4 | Q9UM07 | 20/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22450513 | 0.96 | PADI4 (0.55) | PADI4 | |
| SCHEMBL18975356 | 0.92 | PADI4 (0.53) | PADI4 | |
| SCHEMBL22450526 | 0.91 | PADI4 (0.51) | PADI4 | |
| SCHEMBL18960699 | 0.88 | PADI4 (0.74) | PADI4 | |
| SCHEMBL22450738 | 0.84 | PADI4 (0.52) | PADI4 | |
| SCHEMBL22450536 | 0.82 | PADI4 (0.44) | PADI4 | |
| SCHEMBL18955611 | 0.82 | PADI4 (0.59) | PADI4 | |
| SCHEMBL18960751 | 0.82 | PADI4 (0.59) | PADI4 | |
| SCHEMBL18955572 | 0.82 | PADI4 (0.59) | PADI4 | |
| SCHEMBL18955613 | 0.82 | PADI4 (0.59) | PADI4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3386505-B1 | AZA-BENZIMIDAZOLE INHIBITORS OF PAD4 | PADLOCK THERAPEUTICS INC (US) | 2020-09-23 | — | — | EP | disclosed |
| WO-2017100601-A1 | AZA-BENZIMIDAZOLE INHIBITORS OF PAD4 | PADLOCK THERAPEUTICS, INC. (US) | 2017-06-15 | — | — | WO | disclosed |