Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 8/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.67 |
| ▸ | MAPT | P10636 | 7/20 | 0.62 |
| ▸ | LMNA | P02545 | 6/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.62 |
| ▸ | TSHR | P16473 | 3/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.44 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.44 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.44 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18976171 | 0.81 | MEN1 (0.51) | MEN1KMT2AMAPTLMNASMN1; SMN2 | |
| SCHEMBL18976162 | 0.81 | MEN1 (0.67) | MEN1KMT2AMAPTLMNASMN1; SMN2 | |
| SCHEMBL3685134 | 0.71 | MEN1 (0.54) | MEN1KMT2AMAPTLMNASMN1; SMN2 | |
| SCHEMBL1278809 | 0.71 | MEN1 (0.54) | MEN1KMT2AMAPTLMNASMN1; SMN2 | |
| SCHEMBL5055447 | 0.71 | MEN1 (0.54) | MEN1KMT2AMAPTLMNASMN1; SMN2 | |
| SCHEMBL5062979 | 0.70 | KMT2A (0.52) | MEN1KMT2AMAPTLMNASMN1; SMN2 | |
| SCHEMBL18976161 | 0.69 | MEN1 (0.51) | MEN1KMT2AMAPTLMNASMN1; SMN2 | |
| SCHEMBL4993025 | 0.68 | GRM4 (0.51) | MEN1KMT2AMAPTLMNASMN1; SMN2 | |
| SCHEMBL22588774 | 0.68 | MAPT (0.50) | MEN1KMT2AMAPTLMNASMN1; SMN2 | |
| SCHEMBL28216516 | 0.67 | MAPT (0.63) | MEN1KMT2AMAPTLMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017097224-A1 | AZETIDINE DERIVATIVE, PREPARATION METHOD THEREFOR, AND USE THEREOF | 四川科伦博泰生物医药股份有限公司 | 2017-06-15 | — | — | WO | disclosed |