SCHEMBL18976330

SCHEMBL18976330

CC(C)CC1CNCN1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7118799 0.82
SCHEMBL7118792 0.82
SCHEMBL23802878 0.79 PLG (0.31)
SCHEMBL19975105 0.79 PLG (0.31)
SCHEMBL29184159 0.79 PLG (0.31)
SCHEMBL10219095 0.79 PLG (0.33)
SCHEMBL4725538 0.79 PLG (0.33)
SCHEMBL4725540 0.79 PLG (0.33)
SCHEMBL16520322 0.79
SCHEMBL22482963 0.79

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230381321-A1 CAMPTOTHECIN CONJUGATES SEAGEN INC. 2023-11-30 US disclosed
US-20230257365-A1 SMALL MOLECULE ANDROGEN RECEPTOR PROTEIN DEGRADERS UNIV MICHIGAN REGENTS (US) 2023-08-17 US disclosed
US-20230233690-A1 ANDROGEN RECEPTOR PROTEIN DEGRADERS UNIV MICHIGAN REGENTS (US) 2023-07-27 US disclosed
US-20230159573-A1 SMALL MOLECULE STAT PROTEIN DEGRADERS NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2023-05-25 US disclosed
US-20230158154-A1 CONJUGATES COMPRISING A PHOSPHORUS (V) AND A CAMPTOTHECIN MOIETY TUBULIS GMBH (DE) 2023-05-25 US disclosed
US-20230133671-A1 SETD2 INHIBITORS AND RELATED METHODS AND USES, INCLUDING COMBINATION THERAPIES Epizyme, Inc. (US) 2023-05-04 US disclosed
US-20230036256-A1 CAMPTOTHECIN CONJUGATES SEAGEN INC. 2023-02-02 US disclosed
US-20220033503-A1 Anti PD-L1 Conjugates for Treating Tumors BIRDIE BIOPHARMACEUTICALS, INC. (KY) 2022-02-03 US disclosed
US-20220023437-A1 HUMANIZED ANTI-CD79B ANTIBODIES AND IMMUNOCONJUGATES AND METHODS OF USE GENENTECH, INC. (US) 2022-01-27 US disclosed
US-20210402002-A1 CONJUGATE GLYKOS BIOMEDICAL OY (FI) 2021-12-30 US disclosed
US-11116847-B2 Methylene carbamate linkers for use with targeted-drug conjugates SEAGEN INC. (US) 2021-09-14 US disclosed
US-10981987-B2 Humanized anti-CD79b antibodies and immunoconjugates and methods of use GENENTECH, INC. (US) 2021-04-20 US disclosed
US-10894090-B2 Antibody drug conjugates (ADC) that bind to 191P4D12 proteins AGENSYS, INC. (US) 2021-01-19 US disclosed
US-RE48389-E1 Antibody drug conjugates (ADC) that bind to 191P4D12 proteins AGENSYS, INC. (US) 2021-01-12 US disclosed
US-20200179527-A1 COMPOUNDS FOR TARGETED IMMUNOTHERAPY SHANGHAI BIRDIE BIOTECH, INC. (CN) 2020-06-11 US disclosed
US-20180201679-A1 HUMANIZED ANTI-CD79B ANTIBODIES AND IMMUNOCONJUGATES AND METHODS OF USE GENENTECH INC (US) 2018-07-19 US disclosed
US-20180177888-A1 COMPOUNDS FOR TARGETED IMMUNOTHERAPY SHANGHAI BIRDIE BIOTECH INC. (CN) 2018-06-28 US disclosed
US-20170234883-A1 ANTIBODIES AND IMMUNOCONJUGATES AND USES THEREFOR GENENTECH, INC. (US) 2017-08-17 US disclosed
US-20170166635-A1 CYSTEINE ENGINEERED ANTI-TENB2 ANTIBODIES AND ANTIBODY DRUG CONJUGATES GENENTECH INC (US) 2017-06-15 US disclosed