Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERBB2 | P04626 | 14/20 | 0.43 |
| ▸ | HRAS | P01112 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18976027 | 0.95 | ERBB2 (0.45) | ERBB2HRAS | |
| SCHEMBL18975823 | 0.95 | ERBB2 (0.40) | ERBB2HRASMAPTKDM4EALOX15 | |
| SCHEMBL18975813 | 0.94 | ERBB2 (0.44) | ERBB2HRAS | |
| SCHEMBL18975380 | 0.93 | ERBB2 (0.43) | ERBB2HRAS | |
| SCHEMBL18975700 | 0.89 | ERBB2 (0.45) | ERBB2HRAS | |
| SCHEMBL18976452 | 0.87 | ERBB2 (0.44) | ERBB2HRAS | |
| SCHEMBL27314605 | 0.87 | ERBB2 (0.43) | ERBB2HRASMAPT | |
| SCHEMBL27315464 | 0.86 | ERBB2 (0.43) | ERBB2HRAS | |
| SCHEMBL27307134 | 0.84 | ERBB2 (0.41) | ERBB2HRASMAPT | |
| SCHEMBL27315713 | 0.83 | ERBB2 (0.41) | ERBB2HRASMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017098257-A1 | PBD ANTIBACTERIAL AGENTS | KING'S COLLEGE LONDON (GB) | 2017-06-15 | — | — | WO | disclosed |