Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 11/20 | 0.44 |
| ▸ | FLT1 | P17948 | 10/20 | 0.44 |
| ▸ | RAPGEF4 | Q8WZA2 | 2/20 | 0.43 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18978078 | 0.81 | KDR (0.39) | KDRFLT1RAPGEF4 | |
| SCHEMBL18939052 | 0.81 | CYP19A1 (0.39) | KDRFLT1RAPGEF4P2RX7CYP19A1 | |
| SCHEMBL18939012 | 0.79 | PLAU (0.44) | KDRFLT1 | |
| SCHEMBL18951997 | 0.78 | KDR (0.39) | KDRFLT1RAPGEF4 | |
| Hydrochloric Acid SCHEMBL28647682 | 0.78 | KDR (0.41) | KDRFLT1 | |
| Hydrochloric Acid SCHEMBL18939085 | 0.78 | KDR (0.39) | KDRFLT1RAPGEF4 | |
| SCHEMBL18952053 | 0.76 | KDR (0.41) | KDRFLT1RAPGEF4 | |
| SCHEMBL18939093 | 0.76 | FLT1 (0.46) | KDRFLT1 | |
| SCHEMBL18977465 | 0.76 | KDR (0.44) | KDRFLT1RAPGEF4P2RX7HTR6 | |
| SCHEMBL28658614 | 0.76 | KDR (0.46) | KDRFLT1RAPGEF4CYP19A1HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017096472-A1 | CEPHEM COMPOUNDS, THEIR PRODUCTION AND USE | NAEJA-RGM PHARMACEUTICALS INC. (CA) | 2017-06-15 | — | — | WO | disclosed |